Research
Focus Areas
|
Faculty
|
Research Interests
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| Bagdasarian, M. | Structural biology
|
| Cukier, Robert | Quantum and classical mechanics methods development for simulation
of reaction mechanisms in enzymes
|
| Feig, Michael | Modeling supramolecular assemblies and membrane environments. Protein
structure prediction and refinement |
| Ferguson-Miller, Shelagh | Defining functionally important structural features of protein:protein
interface between cytochrome c and cytochrome oxidase |
| Hausinger, Robert | Structure/function studies of enzymes and biological processes involving metal ions |
| Hoogstraten, Charles | RNA catalysis and RNA-protein interactions; biomolecular NMR and EPR methods and applications |
| Kron, Michael | Drug development |
| Kroos, Lee | Determining the structures of bacterial transcription factors |
| Kuhn, Leslie | Developing computational approaches for protein folding, ligand
interactions, and design |
| Lapidus, Lisa | Study fast folding processes using laser spectroscopy
and microfluidics |
| Levy, Ronald | Computational approaches to protein structure, folding,
dynamics, and ligand binding; structural biology of transcription
and macromolecular machines |
| Maggiora, Gerald | Drug design, ligand-protein interactions, protein structure, SAR |
| Preiss, Jack | Structural biology, evolutionary modeling |
| Seibold, Steve | Computational methods (Molecuar Dynamics, Docking, etc.) to investigate protein structure function relationships in ligand binding and water chain formation necessary for enzyme activity |
| Torng, Eric | Developing algorithms for identifying disulfide bonds given mass
spectral data |
| Vieille, Claire | Studying the determinants of protein thermostability using heperthermophilic
enzymes as models |
| Wei, Guowei | Advanced numerical methods for the structure and dynamics of biological macromolecules |
| Weliky, David | NMR and crystallography for structure determination of viral fusion
peptides and proteins |
| Wenkert, David | Collaborations in drug design in the areas of infectious diseases
and cancer |
| Yan, Honggao | Protein structure, function and dynamics with applications to protein
engineering and structure-based drug design |
Top |
|
Faculty |
Research Interests |
| Adami, Chris | Understanding how the fundamental principles of evolution shape
genomes, populations, and ecosystems |
| Ferguson-Miller, Shelagh | Analysis of evolutionary changes in higher primate cytochrome c
and cytochrome oxidase |
| Getty, Thomas | Evolution of signaling, social behavior and life history strategies |
| Goodman, Erik | The Genetic Algorithms Research and Applications Group
(GARAGe) studies and advances evolutionary computation, building on
principles abstracted from nature |
| Huebner, Marianne | Host-parasite systems in mathematical ecology: statistical issues
in data analysis of microarray experiments; genetic association for
complex traits; biological networks |
| Kuhn, Leslie | Relating structural and conformational changes in proteins to amino
acid mutations |
| Preiss, Jack | Structural biology, evolutionary modeling |
| Sun, Fengzhu | Mutation mechanisms of PCR, microsatellite evolution |
| Torng, Eric | Evaluating and developing algorithms for phylogeny reconstruction |
| Vieille, Claire | Changing enzyme substrate and cofactor specificities, changing enzyme
stability to temperature and pH |
| Top
| |
Systems
Biology | |
| Faculty
| Research Interests |
| Chan, Christina | Integrating various levels of information from genetic expression
to metabolic data |
| Cheng, Hans | Structural and functional genomics of disease resistance in chicken. |
| Cukier, Robert | Modelling kinetics and electrostatic interactions of protein assemblies |
| Harrison, Michael | Physics of sensory thresholds in primates: signal-to-noise factors in theoretical neuroscience |
| Hartmann, William | Test theories of sound localization and binaural hearing against
experiments on human listeners |
| Huebner, Marianne | Host-parasite systems in mathematical ecology: statistical issues
in data analysis of microarray experiments; genetic association for
complex traits; biological networks |
| Kroos, Lee | Molecular mechanisms of signaling and gene regulation during bacterial
development |
| Kuhn, Leslie | Modeling flexibility and folding in proteins by analyzing bond networks |
| Levy, Ronald | Transcriptional regulation and gene expresion, statistical models
for biological networks |
| Maggiora, Gerald | Relational methods in biology and mathematical modeling |
| Shachar-Hill, Yair | We study metabolic networks in plant systems including developing seeds and mycorrhizas |
| Sun, Fengzhu | Interaction networks, protein function |
| Tang, Moxun | Signal transduction pathway leading to the activation of the transcriptional
factor NF-KappaB |
| Tomanek, David | Nanostructures |
| Vieille, Claire | Comparing flexibility in mesophilic and hyperthermophilic proteins
by NMR and molecular dynamics |
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