Quantitative Biology & Modeling Courses
Indexed by Department

Chemical Engineering
Past Courses

Biochemistry and Molecular Biology
  • BCH 960 Genomics and Proteomics of Complex Genetic Systems
    • Provide students with a current overview of developments in the areas of structural and functional genomics/proteomics.
    • Examples from eukaryotic (animal, plant, and fungi) and, in some cases, prokaryotic organisms will be covered.
    • One emphasis will be on the demonstration of available Internet resources.
    • Prerequisites: BCH801 (or instructor approved equivalent)
    • Taught by: Christoph Benning, Dean DellaPenna, Doug Gage, John LaPres, Tim Zacharewski
    • Course: Sect. 1, 2 credits, offered every fall
    • Course: Syllabus
    • Contact: Christoph Benning benning@msu.edu
  • BMB 960/GEN 800/CMB 800 Analysis of Transcriptional Networks
    • Seminar will focus on current examples from literature of network analysis and modeling in bacterial and eukaryotic systems, presented by students and instructors
    • Introductory material tailored for students from both biological and mathematical/statistical areas so both areas will profit.
    • Course will complement a Genetics Symposium to be held in May 2006 on this topic
    • Course: 2 credit course, offered spring 2006
    • Course: Meets Wednesday or Friday, depending on room availability, at 2:30p.m.
    • Complete Course Description
    • Taught by: David Arnosti, Lee Kroos, and Chichia Chiu
    • Contact: David Arnosti arnosti@msu.edu
  • BMB 961 Computational Genomics Laboratory (Graduate Bioinformatics Course)
    • Hands-on course on the computer analysis of DNA and protein sequences as well as microarray data.
    • 50% of class time dedicated to PERL programming techniques to automate and simplify the analysis of large data sets.
    • General topics include:
      1. Introduction to the UNIX operating system
      2. DNA sequence analysis using the GCG package of programs
      3. Assembly of genomic DNA sequencing projects using the Staden software suite
      4. Mutation/SNP analysis using the Staden software suite
      5. Database searching and comparison using Blast
      6. Microarray analysis using Tree View, Cluster and R
      7. Excel and Access databases for data analyses and presentation
      8. Phylogenetic analysis
    • Taught by: Kevin Carr, David DeWitt, Rob Halgren, Marianne Huebner, Jeff Landgraf, Matt Larson, Tao Sang, Curtis Wilkerson
    • Course: 2 credits, offered every spring
    • Lecture/Lab: Wednesday & Fridays 3-4:30pm, Microlab in room 128 Hubbard Hall
    • Enrollment limit: 25 (by permission)
    • Complete Course Description
    • Contact: David DeWitt dewittd@msu.edu

  • BMB961, Advanced Topics
  • BMB 961 (formerly BCH 961), Concepts in Protein Structure Analysis and Modeling
    • One hour lecture per week covers and demonstrates the techniques.
    • Students have two hours of hands-on laboratory work in a project-like setting.
    • Taught by: Michael Feig, Michael Garavito, Robert Halgren, Leslie Kuhn, Kaillathe Padmanabhan, Honggao Yan, and William Wedemeyer
    • Course: 2 credits, offered every fall
    • Complete Course Description
    • Contact: Kaillathe Padmanabhan padmanab@msu.edu

  • BMB 961/CEM 987, Biomolecular Spectroscopy - Theory and Applications
    • Introduces students to the basic principles of biomolecular spectroscopy using a range of techniques.
    • Taught by: Doug Gage, Michael Garavito, Rawle Hollingsworth, John McCracken, G.M. Strasburg, Honggao Yan, David Weliky
    • Course: 3 credits, offered periodically in the fall
    • Contact: Honggao Yan yanh@msu.edu

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Chemical Engineering

  • CHE 883/491, Multidisciplinary Bioprocessing Laboratory (MBL)
    • Open to both undergraduates and graduate students from bioscience, chemistry, and engineering
    • To train students to work together effectively in multidisciplinary teams
    • To teach students advanced experimental techniques related to industrial biotechnology
    • Course: offered Spring 2005
    • Required: Senior or graduate standing in a department related to biotechnology
    • Previous offering Course Description
    • Recitation meets Wednesdays 9:10 - 10:00
    • Lab times will be chosen by each student team
    • Contact: Mark Worden
  • CHE 891-003/PLB 802-002/BMB 960-001
    From Analysis of Metabolism to Systems Biology

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Chemistry

  • CEM 883, Computational Quantum Chemistry
    • Covers computational methods in electronic structure determination of energies, structures and other molecular properties.
    • Taught by: James Harrison
  • CEM 888, Computational Chemistry
    • The course is strongly computationally focused.
    • Computational approaches to the electronic structure of molecules.
    • Reaction dynamics.
    • Molecular dynamics simulations.
    • Biomolecular mechanics.
    • Course: Offered in the spring of odd years
    • Taught by: Robert Cukier, James Harrison, Rawle Hollingsworth, Ned Jackson and Piotr Piecuch
    • Contact: Robert Cukier

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Computer Science and Engineering

  • CSE 231 and CSE 232
    • Provides introduction to programming and data structures.
  • CSE 331
    • Provides more in depth treatment of data structures and algorithum design and analysis.
    • Limited capacity, currently only open to CSE majors.
    • Several prerequisites needed before course can be taken.
  • CSE 480
    • Provides introduction to design and implementation of databases.
    • Perhaps more theoretical than needed for CBM students.
    • Limited capacity, currently only open to CSE majors.
    • Many prerequisites needed before course can be taken.
  • CSE 830
    • Graduate course in design and analysis of algorithms.
    • Beefed up version of CSE 331.
    • Limited capacity, currently only open to CSE graduate students.
    • May be more theoretical and general than what is really needed.
  • CSE 960, spring semester, 2001
    • For this semester, this special topics course will focus on string and tree algorithms covering topics such as string matching, alignment and phylogenetic tree construction.
  • CSE 491, Digital Evolution & Biocomplexity

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Genetics

  • GEN 800, Mass Spectrometry and Its Applications for Functional Genomics
    • To cover the history & theory of several types of mass spectrometry, and encompass literature showing the application of this technology to many aspects of functional genomics, including proteomics, metabolomics, and post-translational modifications.
    • Course: Section 002, offered Spring 2005
    • Meeting time to be arranged for convenience of all participants
    • Contact: Suzanna Hoffmann-Benning
  • HRT 892, Plant Breeding and Genetics Seminar
    • Current topics in structural and functional genomics
    • Goal: To provide a better understanding of these topics through group discussion of key papers and current literature
    • Course: Section1, 1 credit, offered Fall 2004
    • Class meets for 1 hour each week
    • First organizational meeting will be held in A279 Plant and Soil Sciences Bldg., Day & Time TBA
    • Taught by: Mitch McGrath mitchmcg@msu.edu

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Mathematics

  • MATH496-2, Nonlinear Dynamics and Chaos
    • Introduction to dynamical systems with an emphasis on applied models
    • Prerequisites: Mth340,Mth309 or Mth314, Mth421 or Permission of instructor
    • Complete Course Description
    • Taught by Keith Promislow
  • MATH995 Computational Biology I, (Topics in Applied Mathematics)

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Microbiology

  • MIC433, Microbial Genomics
    • Graduate course taught every spring semester.
    • Offers opportunity to explore evolutionary, ecological and functional aspects of microbial genomes.
    • Lecture followed by direct analysis of genes and genomes in computer-based laboratory.
    • Primary focus on genomes of prokaryotes.
    • Taught by: Rob Britton rbritton@msu.edu and Thomas M. Schmidt tschmidt@msu.edu

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Physics and Astronomy

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Plant Biology

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Statistics and Probability

  • STT461, Computations in Probability and Statistics - Spring 2006
    • Review of probability
    • Introduction to computer simulation
    • Intended for upper undergraduate and graduate students
    • Course: 3 credit course
    • Complete Course Description
    • Taught by Dong-Yum Kim
    • kimdong2@msu.edu
  • STT890, Statistical Genetics - Spring 2006
    • Course: Register for 3 credits
    • Taught by: Marianne Huebner huebner@msu.edu
  • STT890, Statistical Analysis of Micorarray Data
    • Covers current topics in the area of design and analysis of gene expression data - Spring 2006
    • Course: Register for 3 credits
    • First Meeting: January 9, 2005, 11:15-12:30, A-506 Wells Hall
    • Course Description
    • Taught by: Marianne Huebner huebner@msu.edu
  • STT890, Statistics in Genetics - Spring 2005
    • Designed for graduate students from both statistics and the biological sciences.
    • Will meet for one hour once a week
    • Course: Register for 1 credit
    • Taught by: Marianne Huebner huebner@msu.edu
  • STT890 (sec.2), Statistical Analysis of Gene Expression Data - Spring 2005
    • Course addresses statistical design and inference methods for microarray experiments
    • Will meet once a week
    • Course: Register in STT890 for 1 credit
    • Complete Course Description
    • Taught by: Marianne Huebner huebner@msu.edu

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